MEDICI-PK - The Virtual Laboratory for Pharmacokinetics

Pharmacokinetics and -dynamics involve the study of the drug-organism interaction, in particular the investigation of absorption, distribution, meta-bolism and excretion (ADME) processes and the effect of the drug on the body.

In recent years, in silico (computational) approaches for the analysis, prediction and optimization of pharmacokinetic and pharmacodynamic processes have attracted considerable attention.

During the past two years CiT has developed a powerful, modular, application-specific and user-friendly virtual laboratory to support modeling, simulation and optimization of physicologically-based pharmacokinetic and mechanics-based pharmacodynamic processes in the context of drug design and risk assessment.

MEDICI-PK brochure

MEDICI-PK has been developed in co-operation with Dr. Wilhelm Huisinga, now at Hamilton Institute, Dublin, Ireland.

First publications can be accessed here:

Software Supported Modelling in Pharmacokinetics

The Virtual Lab Approach to Pharmacokinetics: Design Principles and Concepts